CANCER STEM CELL-LIKE CELLS-DERIVED EXOSOMAL LNCRNA CDKN2B-AS1 PROMOTES BIOLOGICAL CHARACTERISTICS IN THYROID CANCER VIA MIR-122-5P/P4HA1 AXIS

Cancer stem cell-like cells-derived exosomal lncRNA CDKN2B-AS1 promotes biological characteristics in thyroid cancer via miR-122-5p/P4HA1 axis

Introduction: Here, the discussion focused on the function and possible mechanism of cancer stem cell-like cells (CSCs)-derived exosomal CDKN2B-AS1 in thyroid cancer.Methods: Specifically, the bioinformatics analysis, dual-luciferase reporter assay and RT-qPCR were conducted to obtain the expression and regulation of CDKN2B-AS1, and the downstream

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Free Fatty Acid Receptors 2 and 3 as Microbial Metabolite Sensors to Shape Host Health: Pharmacophysiological View

The role of the gut microbiome in human health is becoming apparent.The major functional impact of the gut microbiome is transmitted through the microbial metabolites that are produced in the gut and interact with host cells either in the local gut environment or are absorbed into circulation to impact distant cells/organs.Short-chain fatty acids (

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PENDEKATAN SEL SEDIMEN MENGGUNAICAN CITRA PENGINDERAAN JAUH SEBAGAI DASAR PENATAAN RUANG WILAYAH PESISIR (STUDI KASUS DI PESISIR UTARA PROPINSI JAWA TENGAH)

ABSTRAK Wilayah pesisir adalah wilayah peralihan antara darat dan taut.Terdapat banyak sekali amberdaya alam yang dapat dimanfaatkan oleh manusia, sehiagga perkernbangan wilayah pesisir emakin pesat dan kondisi ini menyebabkan konflik antara berbagai kepentingan manusia di ,ilayah tersebut.Diperlukan pengaturan ruang di wilayah pesisir untuk mengat

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